Coronary Collaterals Predict Improved Survival and Allograft Function in Patients with Coronary Allograft Vasculopathy

Coronary collaterals predict improved survival and allograft function in patients with coronary allograft vasculopathy.

BACKGROUND Despite improvements in the care of patients who have received cardiac transplants, coronary allograft vasculopathy (CAV) remains the most prevalent cause of late allograft failure and cardiac mortality. Few proven therapies are available for this important disease. The presence of coronary collaterals imparts a favorable prognosis in patients with native ischemic heart disease; howe...

Coronary Collaterals Predict Improved Survival and Allograft Function in Patients with Coronary Allograft Vasculopathy Lavine et al: Coronary Allograft Vasculopathy Mediated Cardiomyopathy

Coronary stenting in cardiac allograft vasculopathy.

OBJECTIVE The purpose of this study was to evaluate acute angiographic success, in-hospital complications and long-term outcome after intracoronary stenting in patients with cardiac allograft vasculopathy. BACKGROUND The application of conventional interventional modalities to treat discrete lesions in patients with cardiac allograft vasculopathy is associated with higher procedural morbidity...

IVUS in the Assessment of Coronary Allograft Vasculopathy

Cardiac allograft vasculopathy (CAV) is a unique form of accelerated atherosclerosis and remains the leading cause of late morbidity and mortality in heart transplant patients accounting for 30% mortality at 5 years (Miller et al., 1993), (Taylor et al., 2007). Although the pathogenesis of CAV is not fully elucidated, it seems to result from a complex interplay between immunologic and nonimmuno...

Mitochondrial haplogroups associated with end-stage heart failure and coronary allograft vasculopathy in heart transplant patients.

AIMS Mitochondrial haplogroups are known to influence individual predisposition to a wide spectrum of metabolic and degenerative diseases, including ischaemic cardiovascular diseases. We have examined the influence of the mitochondrial DNA (mtDNA) background on the development of human end-stage heart failure (HF) in patients undergoing heart transplantation. The influence of mtDNA haplogroups ...